Inspired by light

Proven by science

Wound healing

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Accelerating wound healing

At the speed of light

"I used Celluma and noticed a significant reduction in the time it took for my face to heal"
"Ten weeks after surgery, my right ear healed significantly sooner and is now completely healed"
"My patients enjoy a significant reduction in inflammation and bruising as a result of using Celluma"

Give yourself the clear skin you deserve

Celluma Light Therapy is uniquely certified to treat skin wounds

In original research conducted at the renowned Beckman Laser Institute at the University of California, Celluma was clinically proven to accelerate wound closure rates and equal or outperform cold laser with similar optical parameters.

Celluma has medical CE marking in Europe for all FDA indications and for dermatological wound healing as a Class 11A medical device in the European Union. LED therapy with Celluma is ideal for use after surgical procedures to improve healing of incisions or non-healing wounds. LED therapy with Celluma can help reduce patient downtime and fight infections while increasing overall patient satisfaction.

Light therapy has been shown to accelerate tissue repair, reduce wound size, accelerate wound closure and have other beneficial effects. These mechanisms have been shown to promote skin wound healing and reduce pain associated with the healing process. Celluma is indicated for dermal wound healing and is indicated for the treatment of superficial wounds that exist on the outer 2 mm of skin, including normal, acute post-operative and chronic wound healing, including but not limited to diabetic ulcers

The groundbreaking research into low-level light therapy (LLLT), also known as LED therapy, was conducted by NASA's Marshall Space Flight Center out of concern for astronauts who may become injured or ill during extended spaceflight. In response to this health risk, NASA is developing light-emitting diode (LED) technology that promises to deliver light energy deep into the body to promote wound healing and human tissue growth. The therapeutic benefits of LLLT have been demonstrated in thousands of clinical studies, articles, and peer-reviewed literature that show the mechanism of action is cellular uptake of photons (light energy) and increased production of adenosine triphosphate (ATP), a form of energy used by cells to fuel cellular activity. The resulting ATP is used to power metabolic processes that include the synthesis of DNA, RNA and proteins and enzymes needed to repair or regenerate cells.

Low light therapy has been shown to shorten patient recovery time while reducing discomfort and improving overall outcomes. It is ideal after any ablative procedure and before and after surgery for the following reasons:

  • Phototherapy has been shown to accelerate tissue repair, reduce wound size, accelerate erythema resolution, accelerate wound closure and prevent dehiscence¹.
  • Phototherapy before surgery can reduce the incidence of hypertrophic scarring and keloids².
  • Continued postoperative photorejuvenation² (activation of fibroblasts to produce collagen and elastin, stimulation of keratinocytes that produce keratin to give structural firmness to the skin).
  • Prevention of post-inflammatory hyperpigmentation².
  • Activation of mast cells, macrophages and neutrophils can reduce inflammation and protect against infections.
  • Phototherapy is antibacterial. The presence of P acne bacteria can lead to postoperative infections, especially in shoulder surgeries. The use of professional LED light therapy prior to surgery can reduce the presence of these bacteria

 

 

 

 
Studies on wound healing

There are hundreds of studies detailing the benefits of LED light therapy and its positive effects on wound healing, including burns, surgical incisions and diabetic ulcers. Below is an excerpt and summary of Photobiomodulation Therapy for Wound Healing: An Effective, Noninvasive, Phototechnical Approach³. Adv Skin Wound Care. (2019) on Light therapy for wound healing.

Overall aim: To provide background information and explore the evidence for the therapeutic use of light energy treatment for wound healing.

Target Audience: This training is aimed at doctors, physician assistants, nurses with an interest in skin and wound care.

Summary: Provide background information and examine the evidence for the therapeutic use of light energy treatment for wound healing. PubMed was searched for research articles published in the past 5 years using the search terms "photobiomodulation therapy" and "low-frequency laser therapy," and these terms were combined with "wound" using a "human-type" filter. This search found 218 articles about photobiomodulation therapy or low-frequency laser therapy and wound. Of these, only articles on in vivo wound treatment with light treatments were specifically included in this review (n = 11). The effect of treating wounds with low-dose laser therapies was first described more than 50 years ago. Different doses, ranging from 0.1 to 10 J/cm, and wavelengths from 405 to 1000 nm appear to offer therapeutic benefits for a wide range of chronic wounds. Various light energy sources have been used, from LEDs to lasers, which have specific advantages and limitations. The reviewed studies lack consensus on standardized treatment parameters, such as wavelength, dose, and therapeutic outcomes, preventing direct comparison and recommendation of a clinical protocol. Expert opinion is offered based on current research and reported literature. Non-invasive, cost-effective and versatile light devices are an attractive tool for wound care. However, there is an urgent need in the wound care community to develop optimal clinical protocols for use based on well-designed, rigorous clinical trials.

In a 2014 study conducted at the University of California's Beckman LASER Institute titled, " Comparison of Laser and Diode Sources to Accelerate In Vitro Wound Healing with Low-Frequency Light Therapy ," Celluma compared favorably to a low-frequency laser for wound closure. Here is the abstract:

Low-level light therapy has been shown to improve wound healing in vitro. However, clearly defined parameters of the different light sources for this therapy are lacking. The objectives of this study were (1) to determine whether the wavelengths tested were effective for in vitro wound healing and (2) to compare a laser and a light-emitting diode (LED) source with similar wavelengths. We show that the four wavelengths delivered by a laser or LED array enhance in vitro wound healing in A549, U2OS, and PtK2 cells. Enhanced wound healing is mediated by increased cell migration as demonstrated by scratch and transwell wound assays. Cell proliferation was tested using the (3-(4,5-dimethylthiazol-2-yl)-5-(3-car-boxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) (MTS) assay and was generally not involved in the wound healing process. Laser and LED sources were found to be comparable when applied at equal light doses. The measured biological response was similar in most cases. We concluded that the laser wavelength of 652 (5.57 mW∕cm2, 10.02 J∕cm2) and 806 nm (1.30 mW∕cm2, 2.334 J∕cm2) (full 5 nm bandwidth) and the LED wavelength of 637 (5.57 mW∕cm2, 10.02 J∕cm2) and 901 nm (1.30 mW∕cm2, 2.334 J∕cm2) (full bandwidth 17 and 69 nm) induced comparable levels of cell migration and wound closure.

References:

1. Effects ofLED emission on sternotomy incision recovery after myocardial revascularization: a randomized double-blind follow-up study

2. Light emitting diodes (LED) in dermatology. Д. Barolet, MD 2008.

3.Effective, non-invasive, photo-technical approach.

The future of

light therapy

Light therapy has proven to be extremely beneficial and will continue to play a huge role in the future of medicine for the treatment of many conditions, including wound healing.

We invite you to read a few of the published studies to get a taste of what's to come.

"The day may not be far off when most homes will have a light source (most likely an LED device) that will be used for pain, suffering, cuts, bruises, joints and that can also be applied to the hair and even transcranially to the brain1!"

REFERENCE:

1 Hasmi, Osmani et al. The role of low frequency laser therapy in neurorehabilitation.

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